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Prostate Cancer Risk Assessment

Learn more about prostate cancer and our assessment service at the Prostate Health Clinic

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Understanding Prostate Cancer

It's Common
Prostate cancer is the most common cancer diagnosed in men. 1 in 8 men will be diagnosed within their lifetime
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Know you risk factors
Men over 50 years old, prostate cancer in other family members, high fat diets, obesity and smoking can increase the risk of prostate cancer.
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Ethnic Risk Factors
Black men have a 1 in 4 chance of being diagnosed with Prostate Cancer. This risk if 3 times higher than white men.
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Symptoms of Prostate Cancer
Unfortunately Prostate Cancer does not have reliable symptoms. Problems with passing urine, burning sensation when passing urine, blood in the urine, erectile dysfunction may all be early signs of the disease.
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Find it early
When detected early, survival rates are very high. Regretably up to 14% of men still present with incurable metastatic disease. There is currently no screening programme for prostate cancer over opportunistic testing.
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What Prostate Cancer diagnostic service do we offer at the Prostate Health Clinic?

We provide access to cutting edge technology and expert opinion to guide your health journey

Prostate Cancer assessment is 1 of the 5 core pillars of prostate health included in your assessment 

Each assessment includes

  • Prostate Specific Antigen (PSA) test
  • Clinical examination 
  • Exploration of Risk Factors
  • Bi-parametric MRI prostate scan 
  • X2 30 minute consultation with a specialist Urologist 
  • Imaging reviewed by Specialist Radiologists

Personalised prostate cancer risk score 

Support through further investigations and treatments 

Ongoing support for you and your family

We offer Stockholm 3 and Proclarix to improve PSA and MRI confidence in selected patients

Disclaimer – Not included in the prostate health assessment package

How do we assess Prostate Cancer risk at The Prostate Health Clinic

Frequently Asked Questions

In its early stages, prostate cancer often causes no obvious symptoms. When symptoms do appear (usually in more advanced disease), they may include:

  • A weak or slow urinary stream, difficulty starting/stopping urination or frequent urination especially at night 

  • Blood in urine or semen

  • Pain in the hips, back, pelvis, or upper thighs 

  • Erectile dysfunction, painful ejaculation (less common) 

Because these symptoms overlap with benign prostate conditions (like BPH or prostatitis), any urinary symptoms should be evaluated by a clinician to assess its origins.

The exact cause of prostate cancer is not fully understood. However, several risk factors are well established:

  • Age: risk rises significantly after age 50, and most cases are diagnosed in men over 65 

  • Family history / genetics: having a first-degree relative (father, brother) with prostate cancer increases your risk 

  • Race / ethnicity: Black men have higher incidence compated to other ethnic groups

  • Hormonal / metabolic factors and lifestyle: high circulating androgens, obesity, diet high in fat, and metabolic dysfunction may contribute (though data is still evolving) 

Because many factors are beyond control (age, family history), risk reduction efforts focus on modifiable elements (diet, weight, exercise) and early detection in higher-risk men.

Men may be assessed for prostate cancer if they present to a doctor with new prostate symtoms or if they request testing, usualy over the age of 50. 

Testing typically involves all of the following;

  • A history detailing the presence or absence of symtoms and prostate cancer risk factors 
  • A physical examination of the prostate. This involves the passage of a gloved finger through the anus to assess the texture and size of the prostate. The prostate is located within a fingers distance from the anal margin
  • Prostate Specific Antigen (PSA) blood test. This can be raised in prostate cancer.
  • Prostate MRI scan. Provides a detailed view of the prostate and comments up on its size and presence of abnormalities which may ammount to cancer.
 

If the above tests are concerning for prostate cancer then a biopsy of the prostate is offered to clarify the diagnosis. 

Treatment depends on multiple factors: cancer stage, grade, PSA level, patient age, comorbidities, life expectancy, and patient preferences. Common options and considerations include:

  • Active surveillance / watchful waiting: For low-risk, slow-growing cancers, monitoring with PSA, MRI, and repeat biopsies is often chosen to delay or avoid treatment side effects.

  • Radical prostatectomy (surgery to remove the prostate)

  • Radiation therapy (external beam, brachytherapy / seed implants) 

  • Androgen deprivation therapy (ADT/hormonal therapy): Reduces testosterone to slow cancer growth (often used in advanced or combined treatment). Novel hormone treatments further block the action or production of testosterone to boost the effects of ADT.

  • Chemotherapy / targeted therapy / new systemic agents: More often used in advanced/uncurable metastatic disease. This is when the disease has spread away from the prostate to other parts of the body. 

  • Combination treatments: In many occasions two or more treatments are used together (e.g. radiotherapy + hormonal therapy in curable disease or hormone therapy + chemotherapy in metastatic disease)

  • Palliative / supportive care: In cases of advanced disease where cure is not possible, focus shifts to symptom control and quality of life

Each treatment has trade-offs, especially in terms of side effects: urinary incontinence, erectile dysfunction, bowel issues, and changes in quality of life. Patients should discuss expected outcomes and risks in depth with their cancer care team.

Men over 50 (or younger if there’s a family history or higher risk) should discuss PSA testing with their doctor to understand the benefits and limitations before deciding.

Prostate cancer detected early and confined to the prostate can often behave in a very indolent manner. Many men chose to monitor their prostate cancer with Active Surveillance (AS). Strict monitoting of the condition can help identify the correct timing to intervene with treatments which carry a number of long terms side effects. Some men may be able to aviod treatments alltogether. 

A proportion or men are advised to or chose to undergo treatment for prostate cancer confined to the prostate. This can be determined based on the factors such as the grade, stage, PSA level or other health issues. These patients often have a high chance of cure with treatments including prostatectomy or radiotherapy. 

Prostate cancer that has spread to other areas of the body (stage 4 or metastatic disease) unfortunately cannot be cured. The diseasee can be treated or managed with hormonal therapy. Treatments at this stage of the disease are often given in combination and life expectancy can vary, but is often measured in years.

We offer additional tests for prostate cancer diagnostics

Novel prostate cancer biomarkers

The Prostate Health Clinic is proud to offer SELECT patients the supplementary option of cutting edge prostate cancer biomarkers to complement our comprehensive clinic assessment.  
  • Stockholm 3 combines the PSA, protein biomarkers, genetic data and clinical data to  provided an improved risk score compared to PSA alone
  • This can help rule out prostate cancer if your PSA is high especially if your MRI scan is equivocal 
  • It may help prevent the need for prostate biopsies in men with a PSA between 1.5 – 20ng/nL
  • It can help pick up aggressive prostate cancer in men with a low PSA, and rule out aggressive prostate cancer in men with a high PSA. 
  • Furthermore, it provides a traffic light score that can be used to guide future monitoring
  • Proclarix measures 4 key biomarkers; THBS1 (Thrombospondin-1), CTSD (Cathepsin), Total PSA, and Free PSA
  • These results combined with prostate volume  and age provide a Proclarix Risk Score 
  • Particularly helpful for men with a PSA between 2-10ng/nL
  • Has a negative predictive value of 95% for detecting significant prostate cancer and can be helpful in clarifying indeterminate MRI scan results 

Disclaimer – These tests are NOT included in the fixed fee through the Prostate Health Clinic – please ask your urologist for more information

We explore the role for novel biomarkers in the diagnosis or exclusion of prostate caner allongside conventional testing using PSA and MRI prostate imaging. 

Stockholm 3

Proclarix

What are the novel prostate cancer biomarkers?

The Prostate Health Assessment includes:

  • x2 30 minuite appointments with an expert Urologist
  • Urine Dipstick X2
  • Fully Medical History
  • Physical Examination
  • Blood Tests – To explore your health and organ functions
  • Detailed report including findings, investigation or recommendations 

Cutting edge technology 

  • Risk factors assessment 
  • Prostate physical examination 
  • Prostate Specific Antigen (PSA) blood test 
  • Biparametric MRI prostate scan 
  • Detailed history and examination 
  • Height / weight
  • Blood pressure
  • Testosterone level
  • FSH/LH level
  • Medication review
  • Physical examination
  • Questionnaire – SHIIM
  • Testosterone blood analysis + LH/FSH/SHBG
  • History and examination 
  • Height/weight/blood pressure 
  • Cholesterol and HbA1c levels
  • Qrisk3 risk assessment
  • Detailed urinary symptom assessment
  • International Prosate Symtoms Score (IPSS) 
  • Physical examination 
  • Flow rate and post void scan 
  • PSA, renal function blood test
  • Prostate MRI scan (Prostate sizing and anatomical configuration)

Empowering change

We provide you with a detailed prostate health assessment and personalised action plan to help and direct you towards your health goals

Book your holistic and fully inclusive prostate health clinic

Take back control for peace of mind and
£ 1995 All Inclusive Fee
  • Prostate Cancer Risk Assessmet
  • Testosterone Health Assessment
  • Erectile Dysfunction Assessment
  • Male Urinary Symptom Assessment
  • Cardiovascular Health Assessment
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Take control of your prostate health

Looking after your prostate health could save your life. Whether you want peace of mind with a risk assessment or need expert advice on symptoms, we’re here to help.
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